Workstream 1: Att förstå cancerrisk
Identifying cancer risk factors and developing better tools for prevention and early detection.
The Full Spectrum of Risk, Diagnosis, Treatment, Survivorship, and Equity
Connecting Large and Complementary Data Sources
CIRCE brings together researchers from multiple disciplines to study women’s cancers across the full spectrum of risk, diagnosis, treatment, survivorship, and equity.
Our research combines cancer biology with imaging, epidemiology, genomics, psychology, demography, health economics, and register-based science to better understand not only how cancer develops and is treated, but also how it affects women’s lives, families, and society.
A central strength of CIRCE is the ability to connect large and complementary data sources, including registries, biobanks, clinical data, imaging, and molecular data, and to analyze them from a life-course perspective. This makes it possible to ask questions that cannot be answered within a single discipline or dataset alone.
Projects
Selected research projects
CIRCE projects operate at the intersection of biology, gender, clinical care, demographics, socioeconomics, and survivorship. Here we highlight several projects.
Workstreams
Our research is organized into five interconnected workstreams
Together, these work streams reflect CIRCE’s ambition to generate research that is scientifically strong, clinically relevant, and socially meaningful.
Workstream 2: Individanpassad cancerbehandling
Understanding who benefits from treatment, who is harmed, and how care can be made safer and more precise.
Workstream 3: Att leva väl efter cancer
Improving quality of life, resilience, and long-term outcomes for patients and families.
Workstream 4: Att uppnå jämlik cancervård
Reducing disparities in cancer prevention, diagnosis, treatment, and survivorship.
Workstream 5: Framtidens forskning om cancer hos kvinnor
Training the next generation of researchers, fostering collaboration, and translating research into impact.
Publications
Latest publications
CIRCE researchers produce scientific publications, reports, and other research outputs across a wide range of fields relevant to women’s cancers. These include studies in cancer biology, genomics, imaging, psychology, epidemiology, survivorship, and health equity, as well as interdisciplinary work that bridges these areas. Our publications section will highlight both recent outputs and selected key papers that reflect the breadth and aims of CIRCE’s research.
Show all publications| Title | Authors (CIRCE PI's in Bold) | JOURNAL | Date |
|---|---|---|---|
| RECIST 1.1 och PERCIST för bedömning av behandlingssvar vid metastaserad bröstcancer: genomförbarhet och överensstämmelse i en retrospektiv kohortstudie baserad på klinisk praxis ChatGPT can make mistakes. Check important info. |
| Eur J Radiol | september 2026 |
| Spårning av strukturella varianter vid tidig bröstcancer med en högkänslig ctDNA-analys förutsäger återfall efter neoadjuvant behandling: multicenterstudien ALIENOR | Blaye C, Bidard FC, Hue L, Howarth K, Pierga JY, Dalenc F, Jacot W, Djerroudi L, Potonnier W, Dumas V, Lalet C, Maréchal M, Pulido M, Brunet M, Salabert L, Venat L, Maran-Gonzalez A, Saal LH, Franchet C, Birkeälv S, MacGrogan G, Bonnefoi H | ESMO Open | juli 2026 |
| AI-baserade detektionspoäng vid screeningmammografi för tidig upptäckt av bröstcancer | Hickman S, Gialias P, Schurz H, Cossío F, Choi T, Tsirikoglou A, Gustafsson H, Zackrisson S, Strand F. | Radiology | juni 2026 |
| Betydelsen av övervakning för kvinnor med ärftlig risk för bröstcancer: en hermeneutisk fenomenologisk studie | Sjöqvist AS, Zackrisson S, Gårdling J, Bolejko A | J Clin Nurs | maj 2026 |
| NeoCircle: Dynamiken i cirkulerande tumör-DNA före och efter operation förutsäger överlevnad vid neoadjuvant behandlad tidig bröstcancer | George AM, Chen Y, Gladchuk S, Alcaide M, Dalal H, Meng P, Brueffer C, Saghir H, Kimbung S, Aaltonen K, Oton L, Rushton C, Birkeälv S, Jönsson M, Zackrisson S, Skarping I, Förnvik D, Zander L, Honeth G, Woodhouse S, Howarth K, Borg Å, Ehinger A, Malmberg M, Rydén L, Loman N, Saal LH. | EMBO Mol Med | maj 2026 |
| Heterogent behandlingssvar vid metastaserad bröstcancer: diskrepans mellan klassificering med FDG-PET och CT | Cancer Imaging | augusti 2026 | |
| Kulturella faktorers betydelse för användningen av förebyggande hälso- och sjukvård | Bietenbeck J, Maschmann L, Nilsson T, Spika D | Journal of Economic Behavior & Organization | september 2026 |
Funding
Research grants
CIRCE is made possible through a major long-term center grant from Forte and the Swedish Research Council (Vetenskapsrådet). Beyond the center’s core funding, CIRCE researchers are also supported by a broad portfolio of national and international grants. This diverse funding base reflects both the scientific strength of the researchers involved and the importance of the questions CIRCE seeks to address. We are deeply grateful to all current and future funders who make this work possible and who share the ambition to strengthen women’s cancer research for the benefit of patients, families, and societies.